its such a small act, switching hands, that you barely even notice it. its just natural. i use rh reels and it just feels natural to me. i have used lh reels and they just feel weird. i feel like i should be palming the reel with my left hand and it feels very unnatural palming with my right hand.
plus, i cast two handed, over my right shoulder 90% of the time, with my right hand just below the reel and my left hand just above the butt (gives me more control on the cast). so i dont really have to "switch hands" all i do is just bring my left hand up the rod handle and palm the reel, then bring my right hand up and begin my retrieve.