For training/recreational shooting, bullet weight is based on personal preference of recoil characteristics, or what the particular barrel prefers accuracy wise.
For self defense ammunition, Don't waste money on gimmicks. Stick to any of the modern, proven offerings and you'll be fine. Stick to 124 and 147gr projectiles (or 135 in the case of Hornady). The following are safe choices.
Federal HST
Speer G2
Hornady Critical Duty
Win PDX1
Win Ranger (if you can get it)
The 5906 can be a little more picky than more modern striker fired guns, so I'd definitely confirm function with a few boxes of whatever defensive ammunition you choose.
According to Dobyns, that is not quite correct. I emailed and asked for clarification. I think is will be interesting for a lot of people, as everything I see online calls this a graphite rod.
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