What Bob noted is correct. The best auto clears are two-part and contain isocyanates - very nasty buggars that you need to protect yourself from.
I spray it and have a good venting system, but I also wear long gloves and a full-face respirator.
Other than that, I find that finishing with auto clear is pretty easy. I use Flex-Coat syringes to mix small quantities at a time. The clear I use is 2:1 and doesn't need to be reduced (I spray it through a .5mm Iwata Revolution).
I can mix just enough clear to spray 3 or 4 coats on one bait if needed.
The flash time between coats is 15-20 min. so it takes about an hour for the entire process. The clear dries perfect and clear (and will stay clear) without any edge thinning, and also doesn't require lure rotation.
I don't really recommend it unless specifically asked, because it is some nasty stuff, and invariably somebody (perhaps not here ) will jump down my throat for suggesting it, but I'm just relating my experience with it.
Use at your own risk. ;D