I've had this happen in the past as well and something that really helped me was talking to some of the regulars and 'old timers' that I would meet while out on the water.
There is one park lake close to me that I had been visiting for months and have NEVER been able to even get a bite at. I'd tried everthing. Jigs, weightless senkos, topwaters, cranks, jigs. Nothin. Not even a nibble.
I met a guy while fishing one time and he told me that the secret was the color red. The fish wouldn't bite anything that was any other color. He told me to slow reel a red senko across the bottom and it would drive the fish nuts. Sure enough, went and got some red senkos and caught my personal best on the second cast. Now that I know what the fish like, I've never left without landing something.