Depends on the water temp and whether it has been warming or not? For river fishing it is all about wintering holes and their transition from them. Try to find the wintering holes then concentrate on the areas the fish could move to without expending much energy. An example would be a bass is not going to swim from a 15' hole a 1/4 mile up a flat but will rise into the shallow water of the bank beside its hole.
And as for lures 33-39 degree water I would use hair jigs and 2.5" tubes in natural colors. For 39-45 degree water I have had luck with; finesse jigs, shad raps, slow rolled spinnerbaits, suspending crankbaits, and subtle creature baits. Once the water hits 45 degrees I have caught them on everything including topwaters so have at it.
Another thing I have noticed is a shorter bulkier bait works better earlier in the year than a longer skinnier one which is the exact opposite of the summer.
Allen