I have personally or had clients land thousnands of King salmon from 30 to 60 pounds on line as light as 15 pound test with both floro and mono. I have become proficient at most popular knots, done many knot tests on all types of lines. Results of tests have made me switch from one favorite knot to another. Years ago I landed many big fish with light line using an improved clinch, but that doesn't mean a San Diego Jam is not a better knot, because it is. I used a palamar for years before I learned I was tying it wrong. Landed many large fish with it but now tie it correctly, may save me a fish some day. It doesn't hurt to learn and use a knot that tests higher than an old favorite. Likewise a person doesn't have to set a drag with a scale to catch a big fish, but it sure doesn't hurt. Using a scale for setting drags is standard practice in salt water.
I readily admit, that I have lost many big fish over the years to knot failure. The knot is the weakest link, and will fail if to much force is applied. I have yet to have a knot I have tested be 100 percent. Even Bimmini twists will break before the main line does. Most knots will break just above the knot, making people believe it wasn't the knot that broke. In reality when enough force is applied the knot slips a fraction of an inch, causing the line to break where it slipped. I will say I have had more knot failures with floro, than mono, but do use floro when I determine I need to which is way less often than just a few years ago. I have a friend that told me he never had a knot break, I told him it was just like the time he claimed he never missed a big game animal. Not lying, just a short memory. Any one who has fished long enough, has had knot, line, and other equipment failure. Keeping these failures to a minimum has always bee my goal. Landing a large salmon, trout, or saltwater fish with light line is easy most of the time. I have had clients that were poor beginners land salmon more than twice the line strength, even in strong current. The right drag setting and patience is all that is needed. The same angler would never have pulled a double digit bass away from the typical cover a bass lives in. Landing a large bass on light line is another story. I have never landed a double digit bass let alone one on light line. Trying to pull a bass that large out of the middle of a tree would have to stress the line, knot and angler skill to the very maximum. It would be nice to know exactly how much pressure could be applied, and that the very best knot and line are being used. Of course a little luck doesn't hurt.