I generally agree. I am not super familiar with various calibers, ballistics, or ammo specifications even though I have hunted and used firearms since I was 12.
One item not mentioned here is the availability of ammo. Everyone knows that at times, certain ammo becomes very difficult to locate because of demand. A firearm is pretty useless if you don’t have ammo for it. Not saying you should hoard a bunker full of ammo.
I think for this reason, a lot of general big game hunters select calibers such as .270 or 30-06. Generally speaking that ammo seems more widely available than others where I live.