Drawbacks to braid? I guess I can think of a few...you cut your hands testing your knot because it doesn't break, it lasts for years and years so you don't have that fun of replacing your line every 3 months, when you hook a bass in grass it cuts the grass instead of tangling in it so you may leave floating vegetation, it has zero memory so you will not have those cute coils draping down from your rod tip, because of this no memory thing it floats off the spool and through the guides increasing casting distance so you may hit trees every now and then, you will no longer have that heart pumping fear of a breakoff when fighting a bass...geeze, there has to be more, I'm just tired from a long day.
OK, that's enough. Seriously though, there are only 2 drawback (real ones now) that I can think of and one is its visibility and the other is it has no abrasion resistance to rock or shell. And a fluoro leader takes care of both of those. You may have guessed I'm a huge fan of braid, have tried many and my favorite is Power Pro Super Slick. Stuff is amazing.
And I use a blood knot to connect.
found here:
http://www.animatedknots.com/knotlist.php?Categ=home&LogoImage=LogoGrog.jpg&Website=www.animatedknots.com