I will also cast my vote for Santee-Cooper. The Cypress trees hold some huge bass. Mid to late March should see some huge 10+ pound fish as the bass enter the spawn. I already have three days I am planning to fish at the end of the month depending on the moon phase. As for accomodations, Blacks is about as good as it gets.
Lake Murray still host a lot of bass tournaments. However, you have to be good at fishing high pressure, clear water lakes.
A VERY under rated but good lake is Lake Wateree. There is a decent camp at Lake Wateree State Park in Winnsboro. Wateree has tons of docks to skip in the spring and lots of alligator grass.
Once you decide, if you want specific information about the lake and possible areas to fish, hit us up and we will share what we can.