Well, I use the lefthanded reels and like a fool transfer the rod to my left hand to cast(dominant). But I have met a few right handers that have made the change to a lefthanded reel and cast right handed,then retrieve with their left hand. No loss time,no missed hook sets on pick-ups. The proper way to do it could be to have your dominant hand do the casting and your opposite hand do the retrieving. So, you can see even many of the pros have limitations