Lew's love in Texas goes back to the '80s and fishing Mecca Roy's Bait & Tackle in Corpus (also Larry's Tackle Town in Rockport before Larry sold it), and the number of small pro shops that popped up around the state before BPS moved in. We fished these for decades and wondered why anybody would want to buy a Revo, though we understood the $400 Calcutta urge.
That said, Lew's love is alive and well, and it simply defines baitcaster for many.
The only thing that ever sent me to Daiwa was the range of aftermarket spools made for SV reels, and the total dearth of equivalent spools for Lew's reels.
I'm also beyond Meh on Lew's centrifugal brake, because I don't fish the weights that need it.
Specific to the OP's question, Lew's builds off 2 basic frames using different MOC, 3 different brake systems, different spool capacities, finish grades including use of ball bearings to replace bushings. While Doyo builds Lew's reels, and many parts interchange, you'll note many spec differences between Lew's reels and Doyo-built reels for other marques.
Backing up to 1973, Lew's BB-1 was one of those paradigm changes in reel design that happen 3 times/ century and sent every reel maker scrambling, though he didn't patent it before he asked Shimano to build it for him. If he had patented his design, Shimano (and Every other maker) wouldn't have copied it for 18 years.