I've fished with guides many times -- in Florida, Georgia, Texas, Alabama, South Carolina, freshwater, saltwater... and sometimes, you just have no idea what to expect from the guide (and similarly, the guide has no idea who he'll be stuck on the boat with). Some guides are just good fisherman, some are good businessmen, but a truly good guide is both a good fisherman and a good businessman.
With that said, when you're paying for a guide you're paying for their expertise on that body of water so I would strongly recommend listening to them since they fish that area much more than you do. Some guides are more effective at conveying their "suggestions" in a friendly but effective way, and unfortunately there are those who forget that they're in the customer service industry. I've generally been fortunate with the guides I've fished with, but there is one guy in Florida who gave me a good idea of what NOT to do as a guide.
Another guide I've fished with quite a few times told a funny story about a trip he had. The customer insisted on throwing his Rebel crawdad crank all day, in every spot. The guide recommended fishing a worm, and showed the customer that the bass were biting the worm, but the customer didn't listen. At the end of the day, the customer complained to the guide that he didn't catch any fish. What is the guide to do?
To sum up, here's what I'd say...
-- casting and hook setting -- while on the trip, do what's comfortable for you. You're there to fish, not waste time learning a new motion. But remember the input she provided and try it at home when you're not paying by the hour
-- lure selection -- listen to the guide. You're not on your home water, so there's a high probability the guide knows more than you do about that water